D	C150113	EDQM-HC Basic Dose Form Terminology	C149346	Additive Dosage Form	Additive (unspecified)	89	A type of pharmaceutical dose form that may be liquid, semi-solid or solid, to be added to a large volume of diluent, such as in a bath.	A pharmaceutical dose form that is added to a diluent.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42891	Block Dosage Form	Block	49	A type of solid pharmaceutical dose form consisting of a large, compact mass, usually formed by compression of the component material into a cuboid or similar shape.	A solid or semi-solid in the shape of a square or rectangle.
D	C150113	EDQM-HC Basic Dose Form Terminology	C64878	Cachet Dosage Form	Cachet	50	A type of solid pharmaceutical dose form consisting of a disc inside which a single dose of the active substance(s) is enclosed. Capsule is excluded.	A solid composed of dry powdered active and/or inert ingredient(s) covered by an edible shell. The shell consists of two concave pieces of wafer made of flour and water.
D	C150113	EDQM-HC Basic Dose Form Terminology	C25158	Capsule Dosage Form	Capsule	51	A type of solid pharmaceutical dose form consisting of a shell inside which a single dose of the active substance(s) is enclosed. Cachet is excluded.	A solid contained within either a hard or soft soluble shell, usually prepared from gelatin.
D	C150113	EDQM-HC Basic Dose Form Terminology	C45414	Cement Dosage Form	Cement	103	A type of semi-solid pharmaceutical dose form that hardens after application to form a seal or bond.	A base composed of bonding agents intermingled with active and/or inert ingredient(s), which rapidly hardens into a firm mass upon application.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149373	Collodion Dosage Form	Collodion	77	A type of liquid pharmaceutical dose form usually consisting of a solution of pyroxylin in ether and ethanol. (EDQM-HC Code: 77).	Liquid preparation usually containing pyroxylin in a mixture of ether and ethanol.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42898	Concentrated Solution Dosage Form	Concentrate	78	A type of liquid pharmaceutical dose form consisting of a concentrated preparation that must be diluted before administration.	A concentrate which is usually diluted prior to administration and exists as a solution in its final form.
D	C150113	EDQM-HC Basic Dose Form Terminology	C28944	Cream Dosage Form	Cream	71	A type of semi-solid pharmaceutical dose form consisting of an oil-in-water or water-in-oil emulsion. (EDQM-HC Code: 71).	A semi-solid composed of an emulsion of lipids, hydrocarbons, waxes, or polyols in water.
D	C150113	EDQM-HC Basic Dose Form Terminology	C148443	Dispersion Dosage Form	Dispersion	79	A type of liquid pharmaceutical dose form consisting of one or more substances, excluding solid particles and large liquid droplets, that are dispersed in an appropriate liquid vehicle. Liposomes, microbubbles, cells and colloidal dispersions (droplets with a nominal diameter less than approximately 1 micrometre in size) are included; for solid particle dispersions, see 'Suspension'; for non-miscible, large-droplet liquid dispersions, see 'Emulsion'.	A type of liquid pharmaceutical dose form consisting of one or more substances, excluding solid particles and large liquid droplets, that are dispersed in an appropriate liquid vehicle.
D	C150113	EDQM-HC Basic Dose Form Terminology	C29012	Drop Dosage Form	Drops (unspecified)	90	A type of liquid pharmaceutical dose form that may be a dispersion, an emulsion, a solution or a suspension, and that is administered in small volumes by instillation; to be used only when further details of the specific form (e.g. dispersion, emulsion, solution, suspension) are unknown.	A substance intended for administration in a drop-wise fashion.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42913	Emulsion Dosage Form	Emulsion	80	A type of liquid pharmaceutical dose form consisting of a stable dispersion of non-miscible liquids; it consists either of oil droplets in an aqueous continuous phase (oil-in-water emulsion) or aqueous droplets in an oily continuous phase (water-in-oil emulsion); for colloidal dispersions (droplets with a nominal diameter less than approximately 1 micrometre in size), see 'Dispersion'.	A semi-solid composed of at least two immiscible liquids, one of which is dispersed as droplets within the other liquid, and stabilized with one or more emulsifying agents.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42932	Film Dosage Form	Film	52	A type of solid pharmaceutical dose form consisting of a thin, single- or multilayer sheet of material, which usually dissolves or otherwise dissipates in an aqueous environment.	A thin layer of water soluble or insoluble polymer intended to coat the site of administration.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42888	Aerosol Foam Dosage Form	Foam	72	A type of semi-solid pharmaceutical dose form consisting of a large volume of gas dispersed in a liquid or sometimes a solid phase.	A foam that is packaged under pressure and released upon activation of an appropriate valve system.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42934	Gel Dosage Form	Gel	73	A type of semi-solid pharmaceutical dose form consisting of a colloidal dispersion of a liquid in a solid; lipophilic gels (oleogels) usually consist of liquid paraffin with polyethylene or fatty oils gelled with colloidal silica or aluminium or zinc soaps; hydrophilic gels (hydrogels) usually consists of water, glycerol or propylene glycol gelled with suitable gelling agents such as poloxamers, starch, cellulose derivatives, carbomers and magnesium-aluminium silicates. (EDQM-HC Code: 73).	A semi-solid composed of a solid, three dimensional, cross linked matrix of polymers within a liquid, yielding a jelly-like material unable to flow at steady state.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42938	Granule Dosage Form	Granules	53	A type of solid pharmaceutical dose form consisting of dry aggregates of powder particles that are sufficiently resistant to withstand handling. (EDQM-HC Code: 53).	A solid composed of small particles or grains.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42941	Gum Dosage Form	Gum	54	A type of solid pharmaceutical dose form consisting of a basis composed of gum(s) or with a gum-like consistency.	A semi-solid composed of a sticky, mucilaginous polysaccharide.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149558	Herbal Material (Unprocessed) Dosage Form	Herbal material (unprocessed)	114	A type of solid pharmaceutical dose form consisting of whole, broken or fragmented plants or parts of plants (including algae, fungi, lichen) in an unprocessed state, and which may be dried or fresh. Teas, as well as preparations that are processed or formulated into capsules, granules, powders, etc., are excluded.	A type of solid pharmaceutical dose form consisting of whole, broken or fragmented plants or parts of plants (including algae, fungi, lichen) in an unprocessed state, and which may be dried or fresh.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42942	Implant Dosage Form	Implant	55	A type of solid pharmaceutical dose form consisting of a mass with a size and shape suitable for implantation, allowing release of active substance(s) over an extended period of time. (EDQM-HC Code: 55).	A solid intended for insertion securely within the body.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149570	Impregnated Material Dosage Form	Impregnated material	56	A type of solid pharmaceutical dose form consisting of a material onto or into which active substance(s) are absorbed for subsequent release after administration, often over an extended period of time.	A type of solid pharmaceutical dose form consisting of a material onto or into which active substance(s) are absorbed for subsequent release after administration, often over an extended period of time.
D	C150113	EDQM-HC Basic Dose Form Terminology	C60933	Insert Dosage Form	Insert	88	A type of solid pharmaceutical dose form consisting of a material of an appropriate shape and size to be placed inside an orifice of the body, and which dissolves or disintegrates over time. Pessaries and suppositories are excluded.	A solid or semi-solid intended for administration within the body.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149612	Intraruminal Device Dosage Form	Intraruminal device	57	A type of solid pharmaceutical dose form intended for administration to ruminant animals where it is retained in the rumen for release of the active substance(s), usually over an extended period of time.	A type of solid pharmaceutical dose form intended for administration to ruminant animals where it is retained in the rumen for release of the active substance(s), usually over an extended period of time.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149626	Lacquer Dosage Form	Lacquer	81	A type of liquid pharmaceutical dose form consisting of one or more substances dissolved or suspended in a volatile solvent that evaporates to leave a hard coating.	A type of liquid pharmaceutical dose form consisting of one or more substances dissolved or suspended in a volatile solvent that evaporates to leave a hard coating.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42953	Liquid Dosage Form	Liquid	82	A type of liquid pharmaceutical dose form consisting of a pure substance in a liquid state.	A substance in the fluid state of matter having no fixed shape but a fixed volume.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42955	Lozenge Dosage Form	Lozenge	58	A type of solid pharmaceutical dose form consisting of a hard mass formed by moulding or compression, intended to dissolve or disintegrate slowly in the oral cavity when sucked. (EDQM-HC Code: 58).	A solid composed of active and/or inert ingredient(s), sweeteners, other flavorings and mucilage, intended for oral administration.
D	C150113	EDQM-HC Basic Dose Form Terminology	C148552	Lyophilized Dosage Form	Lyophilisate	59	A type of solid pharmaceutical dose form consisting of a powder or disc formed by freeze-drying of a liquid or semi-solid preparation. When referring to a powder, the use of this term is restricted to veterinary medicines.	A type of solid pharmaceutical dose form consisting of a powder or disc formed by freeze-drying of a liquid or semi-solid preparation. When referring to a powder, the use of this term is restricted to veterinary medicines.
D	C150113	EDQM-HC Basic Dose Form Terminology	C148452	Medicinal Gas Dosage Form	Medicinal gas	87	A type of gaseous pharmaceutical dose form consisting of a pure substance or mixture of substances that exist in the form of a gas at normal atmospheric pressure and room temperature.	A type of gaseous pharmaceutical dose form consisting of a pure substance or mixture of substances that exist in the form of a gas at normal atmospheric pressure and room temperature.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42966	Ointment Dosage Form	Ointment	74	A type of semi-solid pharmaceutical dose form consisting of a single-phase basis in which solids or liquids may be dispersed; ointments may be composed of a variety of bases including hydrocarbons, emulsifiers, vegetable oils and animal fats; they may be hydrophobic (bases made from substances such as hard, liquid, or light liquid paraffins, vegetable oils, animal fats, synthetic glycerides, waxes and liquid polyalkylsiloxanes, and which are only able to absorb a small amount of water), hydrophilic (with a water-miscible basis, usually a mixture of liquid and solid macrogols) or water-emulsifying (capable of absorbing larger amounts of water and forming emulsions, with bases containing water-in-oil emulsifiers such as wool alcohols, sorbitan esters, monoglycerides and fatty alcohols, or oil-in-water emulsifiers such as sulfated fatty alcohols, polysorbates, macrogol cetostearyl ether, esters of fatty acids with macrogols). (EDQM-HC Code: 74).	A semi-solid, viscous in texture, that may be composed of a variety of bases including hydrocarbons, emulsifiers or vegetable oils, and mixed with active and/or inert ingredient(s).
D	C150113	EDQM-HC Basic Dose Form Terminology	C42967	Paste Dosage Form	Paste	75	A type of semi-solid pharmaceutical dose form consisting of a large proportion of solid particles dispersed in a hydrophobic or hydrophilic basis.	A semi-solid composed of a large proportion of solids and finely dispersed active and/or inert ingredient(s) in a fat-based vehicle.
D	C150113	EDQM-HC Basic Dose Form Terminology	C60985	Pastille Dosage Form	Pastille	60	A type of solid pharmaceutical dose form consisting of a soft, flexible mass formed by moulding, intended to dissolve or disintegrate slowly in the oral cavity when sucked. (EDQM-HC Code: 60).	A solid or semi-solid composed of a lozenge, that contains active and/or inert ingredient(s) that dissolves when sucked in the mouth.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42968	Patch Dosage Form	Patch	61	A type of solid pharmaceutical dose form consisting of a flexible preparation, with an adhesive layer and a reservoir of active substance(s) that is usually behind a semi-permeable membrane. Plasters are excluded.	A solid composed of an impermeable occlusive backing and a formulation matrix in which the active and/or inert ingredient(s) are dissolved or dispersed; possibly includes an adhesive layer.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42969	Pellet Dosage Form	Pellets	62	A type of solid pharmaceutical dose form consisting of usually cylindrical masses, usually formed by extrusion.	A solid composed of a small granular or compressed mass that contains highly purified active and/or inert ingredient(s).
D	C150113	EDQM-HC Basic Dose Form Terminology	C149755	Pessary Dosage Form	Pessary	63	A type of solid pharmaceutical dose form consisting of a material that is usually ovoid and formed by moulding, of a suitable volume and consistency for insertion into the vagina where it dissolves, disperses or melts. (EDQM-HC Code: 63).	Solid, single-dose preparation usually prepared by molding, of various shapes, usually ovoid, with a volume and consistency suitable for insertion into the vagina to obtain a local effect. It contains one or more active substances dispersed or dissolved in a suitable basis that may be soluble or dispersible in water or may melt at body temperature.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149758	Pillule Dosage Form	Pillules	64	A type of solid pharmaceutical dose form consisting of small spheroids that are sufficiently resistant to withstand handling, used for homeopathic medicine. (EDQM-HC Code: 64).	Solid preparation for homoeopathic use, obtained from sucrose, lactose or other suitable excipients. Pillules may be prepared by impregnation of preformed pillules with a dilution or dilutions of homoeopathic stocks or by progressive addition of these excipients and the addition of a dilution or dilutions of homoeopathic stocks. Pillules are intended for oral or sublingual use.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42970	Plaster Dosage Form	Plaster	65	A type of solid pharmaceutical dose form consisting of a flexible preparation with an adhesive layer containing active substance(s). Patches are excluded.	A semi-solid composed of a soft, smooth mass with relatively thick consistency and strong adhesiveness that becomes solid when dry.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149765	Pouch Dosage Form	Pouch	102	A type of solid pharmaceutical dose form that consists of a small bag that is intended to be placed in a body cavity for release of the active substance(s) contained within. (EDQM-HC Code: 102).	Small bag made of a suitable material containing a single dose of a medicinal product, to be placed in a cavity of the body for release of the active substance(s).
D	C150113	EDQM-HC Basic Dose Form Terminology	C47913	Poultice Dosage Form	Poultice	76	A type of semi-solid pharmaceutical dose form consisting of a moist mass, such as meal, herbs, seeds, etc., usually held within or spread upon an appropriate permeable material or dressing. (EDQM-HC Code: 76).	A semi-solid composed of a soft, moist mass that is made by wetting an absorbent solid substance.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42972	Powder Dosage Form	Powder	66	A type of solid pharmaceutical dose form consisting of dry, finely divided, loose particles, or freeze-dried preparations thereof.	A solid composed of a mixture of dry, finely divided active and/or inert ingredient(s).
D	C150113	EDQM-HC Basic Dose Form Terminology	C149863	Unspecified Premix Dosage Form	Premix (unspecified)	91	A type of specialised pharmaceutical dose form that is used in the preparation of products such as medicated feeding stuffs.	A type of specialized pharmaceutical dose form that is used in the preparation of products such as medicated feeding stuffs.
D	C150113	EDQM-HC Basic Dose Form Terminology	C148548	Radiopharmaceutical Dosage Form	Radiopharmaceutical	92	A type of specialised pharmaceutical dose form that is used in the preparation of radiopharmaceuticals.	A type of specialized pharmaceutical dose form that is used in the preparation of radiopharmaceuticals.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42981	Shampoo Dosage Form	Shampoo	93	A type of liquid (or occasionally semi-solid) pharmaceutical dose form that contains surface-active agents and usually forms a foam after rubbing on the scalp with water. (EDQM-HC code: 93).	A solution or suspension composed of an anionic surfactant and intended for administration to the hair and/or scalp.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42986	Solution Dosage Form	Solution	83	A type of liquid pharmaceutical dose form consisting of one or more substances dissolved in, or miscible with, an appropriate solvent, forming a single-phase liquid.	A clear, homogeneous liquid composed of one or more chemical substances dissolved in a solvent or mixture of mutually miscible solvents.
D	C150113	EDQM-HC Basic Dose Form Terminology	C148549	Solvent Dosage Form	Solvent	84	A type of liquid pharmaceutical dose form consisting of a vehicle that contains no active ingredient itself, and is used to dissolve, disperse or dilute another product.	A type of liquid pharmaceutical dose form consisting of a vehicle that contains no active ingredient itself, and is used to dissolve, disperse or dilute another product.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42989	Spray Dosage Form	Spray (unspecified)	94	A type of pharmaceutical dose form that may be liquid, semi-solid or solid, administered as a dispersion in air; to be used only when further details of the specific form (e.g. solution, suspension, powder) are unknown.	A solution or suspension composed of active and/or inert ingredient(s) in oil or water, typically dispensed from an atomizer or nebulizer.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42991	Stick Dosage Form	Stick	67	A type of solid pharmaceutical dose form consisting of a preparation usually in a cylindrical or conical shape, usually prepared by compression or moulding, intended for insertion in or application to a specific area of the body.	A solid composed active and/or inert ingredient(s) in a long, slender cylindrical shape.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42993	Suppository Dosage Form	Suppository	68	A type of solid pharmaceutical dose form consisting of a material that is usually formed by moulding, of a suitable shape, volume and consistency for insertion into the rectum where it dissolves, disperses or melts. (EQM-HC code: 68).	A solid or semi-solid composed of active and/or inert ingredient(s) in a wax, fat or a glycerin gelatin jelly and that is conical or oval in shape. It is intended to be inserted into a body orifice.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42994	Suspension Dosage Form	Suspension	85	A type of liquid pharmaceutical dose form consisting of one or more substances dispersed in a liquid vehicle; the dispersed substance(s) are solid particles that are practically insoluble in the vehicle.	Insoluble solid particles composed of active and/or inert ingredient(s) that are dispersed in a liquid.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42996	Syrup Dosage Form	Syrup	86	A type of liquid pharmaceutical dose form consisting of a viscous liquid usually with a high concentration of sugar or other sweetening agent. (EDQM-HC code: 86).	A solution or suspension composed of a viscid vehicle that contains a high concentration of sucrose or other sugars and active and/or inert ingredient(s).
D	C150113	EDQM-HC Basic Dose Form Terminology	C17423	Drug Delivery System	System	95	A type of pharmaceutical dose form consisting of one or more components that are used to deliver active substance(s) in a specified manner, usually with a modified release mechanism, after administration to a specified location on or in the body; to be used only where more specific terms are not applicable.	Modern technology, distributed with or as a part of a drug product that allows for the uniform release or targeting of drugs to the body.
D	C150113	EDQM-HC Basic Dose Form Terminology	C42998	Tablet Dosage Form	Tablet	69	A type of solid pharmaceutical dose form consisting of a mass that is formed by compression of uniform volumes of particulate solids, or by other means such as extrusion or moulding. (EDQM-HC code: 69).	A solid composed of a mixture of that active and/or inert ingredient(s) are pressed or compacted together, usually in the form of a relatively flat and round, square or oval shape.
D	C150113	EDQM-HC Basic Dose Form Terminology	C149984	Tea Dosage Form	Tea	70	A type of solid pharmaceutical dose form consisting of one or more herbal drugs intended for preparation of a solution by decoction or maceration, or a lyophilised preparation of such a solution.	A type of solid pharmaceutical dose form consisting of one or more herbal drugs intended for preparation of a solution by decoction or maceration, or a lyophilized preparation of such a solution.
D	C150113	EDQM-HC Basic Dose Form Terminology	C150001	Unknown Dosage Form	Unknown	96	The type of pharmaceutical dose form is unknown, or has unspecified or variable physical characteristics.	The type of pharmaceutical dose form is unknown, or has unspecified or variable physical characteristics.
C	C150112	EDQM-HC Administration Method Terminology	C149578	Inhalation Method of Administration	Inhalation	10	Administration of a pharmaceutical product by breathing it into the lungs, usually via the mouth.	Administration of a pharmaceutical product by breathing it into the lungs, usually via the mouth.
C	C150116	EDQM-HC State of Matter Terminology	C45299	Gas	Gas	100	A state of matter consisting of molecules in an elastic aeriform fluid, separated from one another and with freedom of movement, no independent shape or volume and the ability to expand indefinitely.	A fluid in the gaseous state having neither independent shape nor volume and being able to expand indefinitely.
C	C150116	EDQM-HC State of Matter Terminology	C150000	Unclear State of Matter	Unclear	101	A state of matter of unknown, unspecified or variable physical characteristics.	A state of matter of unknown, unspecified or variable physical characteristics.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149484	Endocervical	Endocervical	105	Relating to the cervix uteri as the intended site of administration.	Relating to the cervix uteri as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13307	Gastric	Gastric	106	Relating to the stomach as the intended site of administration, where direct administration is achieved using an appropriate device.	Relating to the stomach.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13359	Gastrointestinal	Gastroenteral	107	Relating to the stomach or duodenum as the intended site of administration, where direct administration is achieved using an appropriate device.	Pertaining to the stomach and intestines.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C25266	Intestinal	Intestinal	108	Relating to the intestines (duodenum, jejunum, ileum, colon) as the intended site of administration, where direct administration is achieved using an appropriate device.	Of, or related to, or referring to the intestines.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13352	Intraperitoneal	Intraperitoneal	109	Relating to the peritoneal cavity as the intended site of administration.	Relating to the peritoneal cavity as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149702	Oculonasal	Oculonasal	110	Relating to the eyes and nares of a bird as the intended site of administration.	Relating to the eyes and nares of a bird as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C96901	Auricular	Auricular	21	Relating to the ear as the intended site of administration, usually where the pharmaceutical product is intended for action in the auditory canal (external auditory meatus).	Relating to the ear as the intended site of administration, usually where the pharmaceutical product is intended for action in the auditory canal (external auditory meatus).
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149423	Cutaneous/Transdermal	Cutaneous/Transdermal	22	Relating to the skin or its appendages (e.g. hair, nails) as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the skin, within the skin, or systemically after passing through the skin.	Relating to the skin or its appendages (e.g. hair, nails) as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the skin, within the skin, or systemically after passing through the skin.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C41136	Dental	Dental	23	Relating to the teeth as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the tooth, inside the tooth, or around the tooth.	Pertaining to a tooth or teeth, or to odontology.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149494	Environmental	Environmental	24	Relating to the surroundings in which the target of the pharmaceutical product is found, as the intended site of administration, e.g. an enclosed volume of water or air; usually the product disperses in the area and is subsequently taken up by the subject.	Relating to the surroundings in which the target of the pharmaceutical product is found, as the intended site of administration, e.g. an enclosed volume of water or air; usually the product disperses in the area and is subsequently taken up by the subject.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149497	Extracorporeal	Extracorporeal	25	Relating to a body substance or tissue as the intended site of administration, after being removed from the body in order to be treated with the pharmaceutical product and then subsequently returned to the body.	Relating to a body substance or tissue as the intended site of administration, after being removed from the body in order to be treated with the pharmaceutical product and then subsequently returned to the body.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149603	Intramammary	Intramammary	26	Relating to the milk-producing organs (mammae) of a female mammal as the intended site of administration, to describe veterinary-only pharmaceutical products that are administered via the teat canal.	Relating to the milk-producing organs (mammae) of a female mammal as the intended site of administration, to describe veterinary-only pharmaceutical products that are administered via the teat canal.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C96903	Intrauterine	Intrauterine	27	Relating to the cavity of the uterus as the intended site of administration.	Relating to the cavity of the uterus as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149623	Intravesical/Urethral	Intravesical/Urethral	28	Relating to the urinary bladder or the urethra (the urogenital canal, connecting the bladder to the outside of the body) as the intended site of administration.	Relating to the urinary bladder or the urethra as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C27958	Nasal	Nasal	29	Relating to the nose as the intended site of administration, including where the pharmaceutical product is intended for local action in the nasal cavity or for systemic action after absorption through the mucous membrane; the lower respiratory tract is excluded.	In reference to the nose.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C87163	Ocular	Ocular	30	Relating to the eye as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the eye or conjunctiva, around the eye, or within the eye.	Of or relating to the eye.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C25311	Oral	Oral	31	Relating to the mouth as the intended site of administration, but where the pharmaceutical product is administered with the intention of passing into the stomach via the oesophagus; the mucosa of the mouth itself is not the intended site of action (see oromucosal).	Of, or relating to, or affecting, or for use in the mouth.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149731	Oromucosal	Oromucosal	32	Relating to the mouth as the intended site of administration, where the pharmaceutical product is administered with the intention of acting on the mucosa of the mouth, whether for local or systemic use.	Relating to the mouth as the intended site of administration, where the pharmaceutical product is administered with the intention of acting on the mucosa of the mouth, whether for local or systemic use.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C150414	Parenteral	Parenteral	33	Relating to the internal body as the intended site of administration, other than the natural openings and cavities such as the gastrointestinal tract, auditory canal, nasal cavity, lungs, etc.; the pharmaceutical product is usually administered by breaking the skin, such as by injection, infusion, and implantation.	Relating to the internal body as the intended site of administration, other than the natural openings and cavities such as the gastrointestinal tract, auditory canal, nasal cavity, lungs, etc.; the pharmaceutical product is usually administered by breaking the skin, such as by injection, infusion, and implantation.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13304	Pulmonary	Pulmonary	34	Relating to the lungs as the intended site of administration, where the pharmaceutical product is administered, usually by inhalation, for local action in the lower respiratory tract or for systemic action after absorption via the lower respiratory tract.	Relating to the lungs as the intended site of administration, where the pharmaceutical product is administered, usually by inhalation, for local action in the lower respiratory tract or for systemic action after absorption via the lower respiratory tract.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C25224	Rectal	Rectal	35	Relating to the rectum as the intended site of administration, where the pharmaceutical product is administered via the anal canal, for local action in the rectum or for systemic action after absorption via the rectum.	Of or pertaining to the rectum.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13309	Vaginal	Vaginal	36	Relating to the vagina as the intended site of administration, where the pharmaceutical product is administered via the vaginal opening, usually for local action in the vagina but sometimes for systemic action after absorption via the vagina.	Of or relating to the vagina.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C150004	Unknown/Miscellaneous Anatomical Location	Unknown/Miscellaneous	37	Relating to various unspecified parts of the body as the intended site of administration, or where the intended site of administration is unknown or not specified.	Relating to various unspecified parts of the body as the intended site of administration, or where the intended site of administration is unknown or not specified.
C	C150115	EDQM-HC Release Characteristics Terminology	C149427	Delayed Release Mechanism of Action	Delayed	44	Release of the substance(s) at a later time than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method; enteric-coated and other gastro-resistant products are included.	Release of the substance(s) at a later time than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method; enteric-coated and other gastro-resistant products are included.
C	C150115	EDQM-HC Release Characteristics Terminology	C149870	Prolonged Release Mechanism of Action	Prolonged	45	Release of the substance(s) over a longer duration than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method.	Release of the substance(s) over a longer duration than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method.
C	C150115	EDQM-HC Release Characteristics Terminology	C149662	Modified-release Mechanism of Action	Modified	46	Release of the substance(s) in a way that differs from that which would be achieved with a conventional-release product, which is achieved by a special formulation design and/or manufacturing method, but which is not classified as delayed-release or prolonged-release; pulsatile-release products are included.	Release of the substance(s) in a way that differs from that which would be achieved with a conventional-release product, which is achieved by a special formulation design and/or manufacturing method, but which is not classified as delayed-release or prolonged-release; pulsatile-release products are included.
C	C150115	EDQM-HC Release Characteristics Terminology	C149409	Conventional Release Mechanism of Action	Conventional	47	Release of the substance(s) in a way that is not deliberately modified by a special formulation design and/or manufacturing method.	Release of the substance(s) in a way that is not deliberately modified by a special formulation design and/or manufacturing method.
C	C150115	EDQM-HC Release Characteristics Terminology	C150002	Unknown Mechanism of Action	Unknown	48	Release of the substance(s) in a way that is unknown or not specified.	Release of the substance(s) in a way that is unknown or not specified.
C	C150116	EDQM-HC State of Matter Terminology	C45299	Gas	Gas	100	A state of matter consisting of molecules in an elastic aeriform fluid, separated from one another and with freedom of movement, no independent shape or volume and the ability to expand indefinitely.	A fluid in the gaseous state having neither independent shape nor volume and being able to expand indefinitely.
C	C150116	EDQM-HC State of Matter Terminology	C150000	Unclear State of Matter	Unclear	101	A state of matter of unknown, unspecified or variable physical characteristics.	A state of matter of unknown, unspecified or variable physical characteristics.
C	C150116	EDQM-HC State of Matter Terminology	C45300	Solid	Solid	97	A state of matter consisting of molecules in a rigid structure that is resistant to change in shape or volume.	The state in which a substance has no tendency to flow under moderate stress; resists forces (such as compression) that tend to deform it; and retains a definite size and shape.
C	C150116	EDQM-HC State of Matter Terminology	C149895	Semi-solid	Semi-solid	98	A state of matter consisting of molecules in a non-rigid structure that can retain its shape and volume but that is not resistant to such change.	A state of matter consisting of molecules in a non-rigid structure that can retain its shape and volume but that is not resistant to such change.
C	C150116	EDQM-HC State of Matter Terminology	C45298	Liquid	Liquid	99	A state of matter consisting of molecules in a non-rigid structure that retains its volume but conforms to the shape of any container applying pressure to it, and is subject to flow.	A substance in the fluid state of matter having no fixed shape but a fixed volume.
C	C150117	EDQM-HC Transformation Terminology	C64657	Dilute	Dilution	38	Transformation of a concentrate into a liquid of greater volume and lower concentration by mixing it with a specified solvent.	To reduce in strength or concentration, especially by the addition of water.
C	C150117	EDQM-HC Transformation Terminology	C150035	Dispersion Activity	Dispersion	39	Transformation of a solid or gas into a dispersion or suspension by mixing it with a specified liquid.	Transformation of a solid or gas into a dispersion or suspension by mixing it with a specified liquid.
C	C150117	EDQM-HC Transformation Terminology	C113023	Dissolution Mixing	Dissolution	40	Transformation of a solid into a solution by mixing it with a specified liquid.	Mixing by adding solids to agitated liquids.
C	C150117	EDQM-HC Transformation Terminology	C64925	Mix	Mixing	41	Transformation of a product into another product by mixing with a specified product.	To bring or combine together or with something else; add as an additional element or part.
C	C150117	EDQM-HC Transformation Terminology	C149700	No Transformation	No transformation	42	No transformation of the product takes place.	No transformation of the product takes place.
C	C150117	EDQM-HC Transformation Terminology	C150003	Unknown Transformation	Unknown	43	It is unknown whether any transformation of the product takes place.	It is unknown whether any transformation of the product takes place.
A	C150113	EDQM-HC Basic Dose Form Terminology	C148443	Dispersion Dosage Form Category	Dispersion	0079	A type of liquid pharmaceutical dose form consisting of one or more substances, excluding solid particles and large liquid droplets, that are dispersed in an appropriate liquid vehicle. Liposomes, microbubbles, cells and colloidal dispersions (droplets with a nominal diameter less than approximately 1 micrometre in size) are included; for solid particle dispersions, see 'Suspension'; for non-miscible, large-droplet liquid dispersions, see 'Emulsion'.	A type of liquid pharmaceutical dose form consisting of one or more substances, excluding solid particles and large liquid droplets, that are dispersed in an appropriate liquid vehicle.
A	C150113	EDQM-HC Basic Dose Form Terminology	C148452	Medicinal Gas Dosage Form Category	Medicinal gas	0087	A type of gaseous pharmaceutical dose form consisting of a pure substance or mixture of substances that exist in the form of a gas at normal atmospheric pressure and room temperature.	A type of gaseous pharmaceutical dose form consisting of a pure substance or mixture of substances that exist in the form of a gas at normal atmospheric pressure and room temperature.
A	C150113	EDQM-HC Basic Dose Form Terminology	C148548	Radiopharmaceutical Dosage Form Category	Radiopharmaceutical	0092	A type of specialised pharmaceutical dose form that is used in the preparation of radiopharmaceuticals.	A type of specialized pharmaceutical dose form that is used in the preparation of radiopharmaceuticals.
A	C150113	EDQM-HC Basic Dose Form Terminology	C148549	Solvent Dosage Form Category	Solvent	0084	A type of liquid pharmaceutical dose form consisting of a vehicle that contains no active ingredient itself, and is used to dissolve, disperse or dilute another product.	A type of liquid pharmaceutical dose form consisting of a vehicle that contains no active ingredient itself, and is used to dissolve, disperse or dilute another product.
A	C150113	EDQM-HC Basic Dose Form Terminology	C148552	Lyophilized Dosage Form Category	Lyophilisate	0059	A type of solid pharmaceutical dose form consisting of a powder or disc formed by freeze-drying of a liquid or semi-solid preparation. When referring to a powder, the use of this term is restricted to veterinary medicines.	A type of solid pharmaceutical dose form consisting of a powder or disc formed by freeze-drying of a liquid or semi-solid preparation. When referring to a powder, the use of this term is restricted to veterinary medicines.
A	C150113	EDQM-HC Basic Dose Form Terminology	C149346	Additive Dosage Form Category	Additive (unspecified)	0089	A type of pharmaceutical dose form that may be liquid, semi-solid or solid, to be added to a large volume of diluent, such as in a bath.	A type of pharmaceutical dose form that may be liquid, semi-solid or solid, to be added to a large volume of diluent, such as in a bath.
A	C150113	EDQM-HC Basic Dose Form Terminology	C149558	Herbal Material (Unprocessed) Dosage Form Category	Herbal material (unprocessed)	0114	A type of solid pharmaceutical dose form consisting of whole, broken or fragmented plants or parts of plants (including algae, fungi, lichen) in an unprocessed state, and which may be dried or fresh. Teas, as well as preparations that are processed or formulated into capsules, granules, powders, etc., are excluded.	A type of solid pharmaceutical dose form consisting of whole, broken or fragmented plants or parts of plants (including algae, fungi, lichen) in an unprocessed state, and which may be dried or fresh.
A	C150113	EDQM-HC Basic Dose Form Terminology	C149570	Impregnated Material Dosage Form Category	Impregnated material	0056	A type of solid pharmaceutical dose form consisting of a material onto or into which active substance(s) are absorbed for subsequent release after administration, often over an extended period of time.	A type of solid pharmaceutical dose form consisting of a material onto or into which active substance(s) are absorbed for subsequent release after administration, often over an extended period of time.
A	C150113	EDQM-HC Basic Dose Form Terminology	C149612	Intraruminal Device Dosage Form Category	Intraruminal device	0057	A type of solid pharmaceutical dose form intended for administration to ruminant animals where it is retained in the rumen for release of the active substance(s), usually over an extended period of time.	A type of solid pharmaceutical dose form intended for administration to ruminant animals where it is retained in the rumen for release of the active substance(s), usually over an extended period of time.
A	C150113	EDQM-HC Basic Dose Form Terminology	C149626	Lacquer Dosage Form Category	Lacquer	0081	A type of liquid pharmaceutical dose form consisting of one or more substances dissolved or suspended in a volatile solvent that evaporates to leave a hard coating.	A type of liquid pharmaceutical dose form consisting of one or more substances dissolved or suspended in a volatile solvent that evaporates to leave a hard coating.
A	C150113	EDQM-HC Basic Dose Form Terminology	C149863	Unspecified Premix Dosage Form Category	Premix (unspecified)	0091	A type of specialised pharmaceutical dose form that is used in the preparation of products such as medicated feeding stuffs.	A type of specialized pharmaceutical dose form that is used in the preparation of products such as medicated feeding stuffs.
A	C150113	EDQM-HC Basic Dose Form Terminology	C149984	Tea Dosage Form Category	Tea	0070	A type of solid pharmaceutical dose form consisting of one or more herbal drugs intended for preparation of a solution by decoction or maceration, or a lyophilised preparation of such a solution.	A type of solid pharmaceutical dose form consisting of one or more herbal drugs intended for preparation of a solution by decoction or maceration, or a lyophilized preparation of such a solution.
A	C150113	EDQM-HC Basic Dose Form Terminology	C150001	Unknown Dosage Form Category	Unknown	0096	The type of pharmaceutical dose form is unknown, or has unspecified or variable physical characteristics.	The type of pharmaceutical dose form is unknown, or has unspecified or variable physical characteristics.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154383	Aerosol Foam Dosage Form Category	Foam	0072	A type of semi-solid pharmaceutical dose form consisting of a large volume of gas dispersed in a liquid or sometimes a solid phase.	A type of semi-solid pharmaceutical dose form consisting of a large volume of gas dispersed in a liquid or sometimes a solid phase.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154384	Block Dosage Form Category	Block	0049	A type of solid pharmaceutical dose form consisting of a large, compact mass, usually formed by compression of the component material into a cuboid or similar shape.	A type of solid pharmaceutical dose form consisting of a large, compact mass, usually formed by compression of the component material into a cuboid or similar shape.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154406	Cachet Dosage Form Category	Cachet	0050	A type of solid pharmaceutical dose form consisting of a disc inside which a single dose of the active substance(s) is enclosed. Capsule is excluded.	A type of solid pharmaceutical dose form consisting of a disc inside which a single dose of the active substance(s) is enclosed. Capsule is excluded.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154433	Capsule Dose Form Category	Capsule	0051	A type of solid pharmaceutical dose form consisting of a shell inside which a single dose of the active substance(s) is enclosed. Cachet is excluded.	A type of solid pharmaceutical dose form consisting of a shell inside which a single dose of the active substance(s) is enclosed. Cachet is excluded.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154434	Cement Dosage Form Category	Cement	0103	A type of semi-solid pharmaceutical dose form that hardens after application to form a seal or bond.	A type of semi-solid pharmaceutical dose form that hardens after application to form a seal or bond.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154435	Collodion Dosage Form Category	Collodion	0077	A type of liquid pharmaceutical dose form usually consisting of a solution of pyroxylin in ether and ethanol.	A type of liquid pharmaceutical dose form usually consisting of a solution of pyroxylin in ether and ethanol.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154437	Concentrated Solution Dosage Form Category	Concentrate	0078	A type of liquid pharmaceutical dose form consisting of a concentrated preparation that must be diluted before administration.	A type of liquid pharmaceutical dose form consisting of a concentrated preparation that must be diluted before administration.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154438	Cream Dosage Form Category	Cream	0071	A type of semi-solid pharmaceutical dose form consisting of an oil-in-water or water-in-oil emulsion.	A type of semi-solid pharmaceutical dose form consisting of an oil-in-water or water-in-oil emulsion.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154464	Drop Dosage Form Category	Drops (unspecified)	0090	A type of liquid pharmaceutical dose form that may be a dispersion, an emulsion, a solution or a suspension, and that is administered in small volumes by instillation; to be used only when further details of the specific form (e.g. dispersion, emulsion, solution, suspension) are unknown.	A type of liquid pharmaceutical dose form that may be a dispersion, an emulsion, a solution or a suspension, and that is administered in small volumes by instillation; to be used only when further details of the specific form (e.g. dispersion, emulsion, solution, suspension) are unknown.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154465	Drug Delivery System Category	System	0095	A type of pharmaceutical dose form consisting of one or more components that are used to deliver active substance(s) in a specified manner, usually with a modified release mechanism, after administration to a specified location on or in the body; to be used only where more specific terms are not applicable.	A type of pharmaceutical dose form consisting of one or more components that are used to deliver active substance(s) in a specified manner, usually with a modified release mechanism, after administration to a specified location on or in the body; to be used only where more specific terms are not applicable.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154466	Emulsion Dosage Form Category	Emulsion	0080	A type of liquid pharmaceutical dose form consisting of a stable dispersion of non-miscible liquids; it consists either of oil droplets in an aqueous continuous phase (oil-in-water emulsion) or aqueous droplets in an oily continuous phase (water-in-oil emulsion); for colloidal dispersions (droplets with a nominal diameter less than approximately 1 micrometre in size), see 'Dispersion'.	A type of liquid pharmaceutical dose form consisting of a stable dispersion of non-miscible liquids; it consists either of oil droplets in an aqueous continuous phase (oil-in-water emulsion) or aqueous droplets in an oily continuous phase (water-in-oil emulsion); for colloidal dispersions (droplets with a nominal diameter less than approximately 1 micrometre in size), see 'Dispersion'.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154467	Film Dosage Form Category	Film	0052	A type of solid pharmaceutical dose form consisting of a thin, single- or multilayer sheet of material, which usually dissolves or otherwise dissipates in an aqueous environment.	A type of solid pharmaceutical dose form consisting of a thin, single- or multilayer sheet of material, which usually dissolves or otherwise dissipates in an aqueous environment.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154468	Gel Dosage Form Category	Gel	0073	A type of semi-solid pharmaceutical dose form consisting of a colloidal dispersion of a liquid in a solid; lipophilic gels (oleogels) usually consist of liquid paraffin with polyethylene or fatty oils gelled with colloidal silica or aluminium or zinc soaps; hydrophilic gels (hydrogels) usually consists of water, glycerol or propylene glycol gelled with suitable gelling agents such as poloxamers, starch, cellulose derivatives, carbomers and magnesium-aluminium silicates.	A type of semi-solid pharmaceutical dose form consisting of a colloidal dispersion of a liquid in a solid; lipophilic gels (oleogels) usually consist of liquid paraffin with polyethylene or fatty oils gelled with colloidal silica or aluminium or zinc soaps; hydrophilic gels (hydrogels) usually consists of water, glycerol or propylene glycol gelled with suitable gelling agents such as poloxamers, starch, cellulose derivatives, carbomers and magnesium-aluminium silicates.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154480	Granule Dosage Form Category	Granules	0053	A type of solid pharmaceutical dose form consisting of dry aggregates of powder particles that are sufficiently resistant to withstand handling.	A type of solid pharmaceutical dose form consisting of dry aggregates of powder particles that are sufficiently resistant to withstand handling.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154491	Gum Dosage Form Category	Gum	0054	A type of solid pharmaceutical dose form consisting of a basis composed of gum(s) or with a gum-like consistency.	A type of solid pharmaceutical dose form consisting of a basis composed of gum(s) or with a gum-like consistency.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154497	Implant Dosage Form Category	Implant	0055	A type of solid pharmaceutical dose form consisting of a mass with a size and shape suitable for implantation, allowing release of active substance(s) over an extended period of time.	A type of solid pharmaceutical dose form consisting of a mass with a size and shape suitable for implantation, allowing release of active substance(s) over an extended period of time.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154518	Insert Dosage Form Category	Insert	0088	A type of solid pharmaceutical dose form consisting of a material of an appropriate shape and size to be placed inside an orifice of the body, and which dissolves or disintegrates over time. Pessaries and suppositories are excluded.	A type of solid pharmaceutical dose form consisting of a material of an appropriate shape and size to be placed inside an orifice of the body, and which dissolves or disintegrates over time. Pessaries and suppositories are excluded.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154551	Liquid Dose Form Category	Liquid	0082	A type of liquid pharmaceutical dose form consisting of a pure substance in a liquid state.	A type of liquid pharmaceutical dose form consisting of a pure substance in a liquid state.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154554	Lozenge Dosage Form Category	Lozenge	0058	A type of solid pharmaceutical dose form consisting of a hard mass formed by moulding or compression, intended to dissolve or disintegrate slowly in the oral cavity when sucked.	A type of solid pharmaceutical dose form consisting of a hard mass formed by moulding or compression, intended to dissolve or disintegrate slowly in the oral cavity when sucked.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154557	Ointment Dosage Form Category	Ointment	0074	A type of semi-solid pharmaceutical dose form consisting of a single-phase basis in which solids or liquids may be dispersed; ointments may be composed of a variety of bases including hydrocarbons, emulsifiers, vegetable oils and animal fats; they may be hydrophobic (bases made from substances such as hard, liquid, or light liquid paraffins, vegetable oils, animal fats, synthetic glycerides, waxes and liquid polyalkylsiloxanes, and which are only able to absorb a small amount of water), hydrophilic (with a water-miscible basis, usually a mixture of liquid and solid macrogols) or water-emulsifying (capable of absorbing larger amounts of water and forming emulsions, with bases containing water-in-oil emulsifiers such as wool alcohols, sorbitan esters, monoglycerides and fatty alcohols, or oil-in-water emulsifiers such as sulfated fatty alcohols, polysorbates, macrogol cetostearyl ether, esters of fatty acids with macrogols).	A type of semi-solid pharmaceutical dose form consisting of a single-phase basis in which solids or liquids may be dispersed; ointments may be composed of a variety of bases including hydrocarbons, emulsifiers, vegetable oils and animal fats; they may be hydrophobic (bases made from substances such as hard, liquid, or light liquid paraffins, vegetable oils, animal fats, synthetic glycerides, waxes and liquid polyalkylsiloxanes, and which are only able to absorb a small amount of water), hydrophilic (with a water-miscible basis, usually a mixture of liquid and solid macrogols) or water-emulsifying (capable of absorbing larger amounts of water and forming emulsions, with bases containing water-in-oil emulsifiers such as wool alcohols, sorbitan esters, monoglycerides and fatty alcohols, or oil-in-water emulsifiers such as sulfated fatty alcohols, polysorbates, macrogol cetostearyl ether, esters of fatty acids with macrogols).
A	C150113	EDQM-HC Basic Dose Form Terminology	C154559	Paste Dosage Form Category	Paste	0075	A type of semi-solid pharmaceutical dose form consisting of a large proportion of solid particles dispersed in a hydrophobic or hydrophilic basis.	A type of semi-solid pharmaceutical dose form consisting of a large proportion of solid particles dispersed in a hydrophobic or hydrophilic basis.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154562	Pastille Dosage Form Category	Pastille	0060	A type of solid pharmaceutical dose form consisting of a soft, flexible mass formed by moulding, intended to dissolve or disintegrate slowly in the oral cavity when sucked.	A type of solid pharmaceutical dose form consisting of a soft, flexible mass formed by moulding, intended to dissolve or disintegrate slowly in the oral cavity when sucked.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154587	Patch Dosage Form Category	Patch	0061	A type of solid pharmaceutical dose form consisting of a flexible preparation, with an adhesive layer and a reservoir of active substance(s) that is usually behind a semi-permeable membrane. Plasters are excluded.	A type of solid pharmaceutical dose form consisting of a flexible preparation, with an adhesive layer and a reservoir of active substance(s) that is usually behind a semi-permeable membrane. Plasters are excluded.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154590	Pellet Dosage Form Category	Pellets	0062	A type of solid pharmaceutical dose form consisting of usually cylindrical masses, usually formed by extrusion.	A type of solid pharmaceutical dose form consisting of usually cylindrical masses, usually formed by extrusion.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154591	Pessary Dosage Form Category	Pessary	0063	A type of solid pharmaceutical dose form consisting of a material that is usually ovoid and formed by moulding, of a suitable volume and consistency for insertion into the vagina where it dissolves, disperses or melts.	A type of solid pharmaceutical dose form consisting of a material that is usually ovoid and formed by moulding, of a suitable volume and consistency for insertion into the vagina where it dissolves, disperses or melts.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154592	Pillule Dosage Form Category	Pillules	0064	A type of solid pharmaceutical dose form consisting of small spheroids that are sufficiently resistant to withstand handling, used for homeopathic medicine.	A type of solid pharmaceutical dose form consisting of small spheroids that are sufficiently resistant to withstand handling, used for homeopathic medicine.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154593	Plaster Dosage Form Category	Plaster	0065	A type of solid pharmaceutical dose form consisting of a flexible preparation with an adhesive layer containing active substance(s). Patches are excluded.	A type of solid pharmaceutical dose form consisting of a flexible preparation with an adhesive layer containing active substance(s). Patches are excluded.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154594	Pouch Dosage Form Category	Pouch	0102	A type of solid pharmaceutical dose form that consists of a small bag that is intended to be placed in a body cavity for release of the active substance(s) contained within.	A type of solid pharmaceutical dose form that consists of a small bag that is intended to be placed in a body cavity for release of the active substance(s) contained within.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154595	Poultice Dosage Form Category	Poultice	0076	A type of semi-solid pharmaceutical dose form consisting of a moist mass, such as meal, herbs, seeds, etc., usually held within or spread upon an appropriate permeable material or dressing.	A type of semi-solid pharmaceutical dose form consisting of a moist mass, such as meal, herbs, seeds, etc., usually held within or spread upon an appropriate permeable material or dressing.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154596	Powder Dosage Form Category	Powder	0066	A type of solid pharmaceutical dose form consisting of dry, finely divided, loose particles, or freeze-dried preparations thereof.	A type of solid pharmaceutical dose form consisting of dry, finely divided, loose particles, or freeze-dried preparations thereof.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154597	Shampoo Dosage Form Category	Shampoo	0093	A type of liquid (or occasionally semi-solid) pharmaceutical dose form that contains surface-active agents and usually forms a foam after rubbing on the scalp with water.	A type of liquid (or occasionally semi-solid) pharmaceutical dose form that contains surface-active agents and usually forms a foam after rubbing on the scalp with water.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154598	Solution Dosage Form Category	Solution	0083	A type of liquid pharmaceutical dose form consisting of one or more substances dissolved in, or miscible with, an appropriate solvent, forming a single-phase liquid.	A type of liquid pharmaceutical dose form consisting of one or more substances dissolved in, or miscible with, an appropriate solvent, forming a single-phase liquid.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154599	Spray Dosage Form Category	Spray (unspecified)	0094	A type of pharmaceutical dose form that may be liquid, semi-solid or solid, administered as a dispersion in air; to be used only when further details of the specific form (e.g. solution, suspension, powder) are unknown.	A type of pharmaceutical dose form that may be liquid, semi-solid or solid, administered as a dispersion in air; to be used only when further details of the specific form (e.g. solution, suspension, powder) are unknown.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154600	Stick Dosage Form Category	Stick	0067	A type of solid pharmaceutical dose form consisting of a preparation usually in a cylindrical or conical shape, usually prepared by compression or moulding, intended for insertion in or application to a specific area of the body.	A type of solid pharmaceutical dose form consisting of a preparation usually in a cylindrical or conical shape, usually prepared by compression or moulding, intended for insertion in or application to a specific area of the body.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154601	Suppository Dosage Form Category	Suppository	068	A type of solid pharmaceutical dose form consisting of a material that is usually formed by moulding, of a suitable shape, volume and consistency for insertion into the rectum where it dissolves, disperses or melts.	A type of solid pharmaceutical dose form consisting of a material that is usually formed by moulding, of a suitable shape, volume and consistency for insertion into the rectum where it dissolves, disperses or melts.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154602	Suspension Dosage Form Category	Suspension	085	A type of liquid pharmaceutical dose form consisting of one or more substances dispersed in a liquid vehicle; the dispersed substance(s) are solid particles that are practically insoluble in the vehicle.	A type of liquid pharmaceutical dose form consisting of one or more substances dispersed in a liquid vehicle; the dispersed substance(s) are solid particles that are practically insoluble in the vehicle.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154604	Syrup Dosage Form Category	Syrup	0086	A type of liquid pharmaceutical dose form consisting of a viscous liquid usually with a high concentration of sugar or other sweetening agent.	A type of liquid pharmaceutical dose form consisting of a viscous liquid usually with a high concentration of sugar or other sweetening agent.
A	C150113	EDQM-HC Basic Dose Form Terminology	C154605	Tablet Dosage Form Category	Tablet	0069	A type of solid pharmaceutical dose form consisting of a mass that is formed by compression of uniform volumes of particulate solids, or by other means such as extrusion or moulding.	A type of solid pharmaceutical dose form consisting of a mass that is formed by compression of uniform volumes of particulate solids, or by other means such as extrusion or moulding.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C149365	Oral Cachet Dosage Form	Cachet	10209000	Solid discoid preparation consisting of a wafer enclosing a unit dose intended for oral use.	Solid discoid preparation consisting of a wafer enclosing a unit dose intended for oral use.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C149373	Collodion Dosage Form	Collodion	10520000	Liquid preparation usually containing pyroxylin in a mixture of ether and ethanol. When applied to the skin, the preparation forms a flexible film on the site of application.	Liquid preparation usually containing pyroxylin in a mixture of ether and ethanol. When applied to the skin, the preparation forms a flexible film on the site of application.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C149755	Pessary Dosage Form	Pessary	10909000	Solid, single-dose preparation usually prepared by moulding, of various shapes, usually ovoid, with a volume and consistency suitable for insertion into the vagina to obtain a local effect. It contains one or more active substances dispersed or dissolved in a suitable basis that may be soluble or dispersible in water or may melt at body temperature.	Solid, single-dose preparation usually prepared by molding, of various shapes, usually ovoid, with a volume and consistency suitable for insertion into the vagina to obtain a local effect. It contains one or more active substances dispersed or dissolved in a suitable basis that may be soluble or dispersible in water or may melt at body temperature.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C149758	Pillule Dosage Form	Pillules	10231000	Solid preparation for homoeopathic use, obtained from sucrose, lactose or other suitable excipients. Pillules may be prepared by impregnation of preformed pillules with a dilution or dilutions of homeopathic stocks or by progressive addition of these excipients and the addition of a dilution or dilutions of homeopathic stocks. Pillules are intended for oral or sublingual use.	Solid preparation for homoeopathic use, obtained from sucrose, lactose or other suitable excipients. Pillules may be prepared by impregnation of preformed pillules with a dilution or dilutions of homoeopathic stocks or by progressive addition of these excipients and the addition of a dilution or dilutions of homoeopathic stocks. Pillules are intended for oral or sublingual use.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C149765	Pouch Dosage Form	Pouch	30047500	Small bag made of a suitable material containing a single dose of a medicinal product, to be placed in a cavity of the body for release of the active substance(s).	Small bag made of a suitable material containing a single dose of a medicinal product, to be placed in a cavity of the body for release of the active substance(s).
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C28944	Cream Dosage Form	Cream	10502000	Semi-solid single-dose or multidose preparation of homogeneous appearance consisting of a lipophilic phase and an aqueous phase, one of which is finely dispersed in the other. Active substance(s) are dissolved or dispersed in the basis, which may be hydrophilic or hydrophobic. Creams are intended for cutaneous use. In certain cases, transdermal delivery may be obtained.	A semi-solid composed of an emulsion of lipids, hydrocarbons, waxes, or polyols in water.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42934	Gel Dosage Form	Gel	10503000	Semi-solid single-dose or multidose preparation consisting of a single-phase basis of liquids gelled by a suitable gelling agent, intended for cutaneous use. Active substance(s) are dissolved or dispersed in the basis, which may be hydrophilic or hydrophobic.	A semi-solid composed of a solid, three dimensional, cross linked matrix of polymers within a liquid, yielding a jelly-like material unable to flow at steady state.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42938	Granule Dosage Form	Granules	10204000	Solid single-dose or multidose preparation consisting of solid, dry aggregates of powder particles that are sufficiently resistant to withstand handling. Granules are intended for oral use to release active substance(s) in the gastrointestinal fluids by a rate depending essentially on the intrinsic properties of the active substance(s) (conventional release). They may be swallowed as such and/or chewed before swallowing, and some may also be dissolved or dispersed in water or another suitable liquid before oral administration. Granules for oral solution and Granules for oral suspension are excluded.	A solid composed of small particles or grains.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42942	Implant Dosage Form	Implant	11301000	Solid sterile preparation of a size and shape suitable for implantation. It may be prepared by moulding or other means other than compression. Each implant is presented in a sterile container that may be provided with an administration device. Implants are intended for release over an extended period of time in order to obtain local or systemic effect. 'Implantation tablet', 'Implantation chain' and 'Implantation matrix' are excluded.	A solid intended for insertion securely within the body.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42955	Lozenge Dosage Form	Lozenge	10321000	Solid single-dose preparation intended to be sucked to obtain, usually, a local effect in the oral cavity and the throat. Lozenges are hard preparations prepared by moulding. They usually contain flavouring and sweetening agents. Lozenges dissolve or disintegrate slowly when sucked.	A solid composed of active and/or inert ingredient(s), sweeteners, other flavorings and mucilage, intended for oral administration.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42966	Ointment Dosage Form	Ointment	10504000	Semi-solid single-dose or multidose preparation consisting of a single-phase basis in which solids or liquids may be dispersed. Active substance(s) are dissolved or dispersed in the basis, which may be hydrophilic, hydrophobic or water-emulsifying. Ointments are intended for cutaneous use. In certain cases, transdermal delivery may be obtained.	A semi-solid, viscous in texture, that may be composed of a variety of bases including hydrocarbons, emulsifiers or vegetable oils, and mixed with active and/or inert ingredient(s).
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42981	Shampoo Dosage Form	Shampoo	10508000	Liquid or, occasionally, semi-solid, usually multidose preparation intended for application to the scalp by rubbing and subsequent washing away with water. Upon rubbing with water, shampoos usually form foam. Shampoos are solutions, suspensions or emulsions containing surface-active agents.	A solution or suspension composed of an anionic surfactant and intended for administration to the hair and/or scalp.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42993	Suppository Dosage Form	Suppository	11013000	Solid single-dose preparation of a shape, size and consistency suitable for rectal use, containing active substance(s) dispersed or dissolved in a suitable basis that may be soluble or dispersible in water or may melt at body temperature.	A solid or semi-solid composed of active and/or inert ingredient(s) in a wax, fat or a glycerin gelatin jelly and that is conical or oval in shape. It is intended to be inserted into a body orifice.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42996	Syrup Dosage Form	Syrup	10117000	Liquid single-dose or multidose aqueous preparation characterised by a sweet taste and a viscous consistency and usually containing aromatic or other flavouring agents, intended for oral use. Each dose from a multidose container is administered by means of a device suitable for measuring the prescribed volume, generally 5 mL or multiples thereof.	A solution or suspension composed of a viscid vehicle that contains a high concentration of sucrose or other sugars and active and/or inert ingredient(s).
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42998	Tablet Dosage Form	Tablet	10219000	Solid single-dose uncoated preparation obtained by compressing uniform volumes of particulate solids or by other means such as extrusion or moulding. Tablets include single-layer tablets resulting from a single compression of particles and multi-layer tablets consisting of concentric or parallel layers obtained by successive compressions of particles of different composition. Tablets are intended for oral use to release active substance(s) in the gastrointestinal fluids by a rate depending essentially on the intrinsic properties of active substance(s) (conventional release).	A solid composed of a mixture of that active and/or inert ingredient(s) are pressed or compacted together, usually in the form of a relatively flat and round, square or oval shape.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C60985	Pastille Dosage Form	Pastille	10323000	Solid single-dose preparation intended to be sucked to obtain, usually, a local effect in the oral cavity and the throat. Pastilles are soft, flexible preparations prepared by moulding of mixtures containing natural or synthetic polymers or gums and sweeteners. They dissolve or disintegrate slowly when sucked.	A solid or semi-solid composed of a lozenge, that contains active and/or inert ingredient(s) that dissolves when sucked in the mouth.
A	C150107	EDQM-HC Routes and Methods of Administration Terminology	C111326	Transmammary Route of Administration	Transmammary	20082000	Exposure of a breast-feeding infant to a medicinal product administered to the lactating mother. Comment: This term is not intended to describe an authorized route of administration for use in marketing aurhoriations, and does not cover intentional administration of a medicinal product to a breastfeeding infant. It is intended for use in adverse eveent reporting for pharmacovigilance purposes.	Administration into the body through colostrum or milk.
A	C150105	EDQM-HC Combined Term Terminology	C153578	Powder and Solvent for Suspension for Injection in Multidose Container	Powder and solvent for suspension for injection in multidose container	13108000	Medicinal product consisting of a powder and solvent for suspension for injection presented in a multidose container; usually the powder is presented in the multidose container while the solvent is presented in a separate container, and is added to the powder in order to prepare the suspension for injection in the multidose container.	Medicinal product consisting of a powder and solvent for suspension for injection presented in a multidose container; usually the powder is presented in the multidose container while the solvent is presented in a separate container, and is added to the powder in order to prepare the suspension for injection in the multidose container.
A	C150105	EDQM-HC Combined Term Terminology	C153625	Solution for Injection in Multidose Container	Solution for injection in multidose container	13109000	Medicinal product consisting of a solution for injection presented in a multidose container.	Medicinal product consisting of a solution for injection presented in a multidose container.
A	C150105	EDQM-HC Combined Term Terminology	C153627	Suspension for Injection in Multidose Container	Suspension for injection in multidose container	13110000	Medicinal product consisting of a suspension for injection presented in a multidose container.	Medicinal product consisting of a suspension for injection presented in a multidose container.
D	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C149933	Solution for Spray Dosage Form	Solution for spray	13034000	Liquid preparation consisting of a solution intended for use in the preparation of a spray.	Liquid preparation consisting of a solution intended for use in the preparation of a spray.
D	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42990	Spray Suspension Dosage Form	Suspension for spray	13038000	Liquid preparation consisting of a suspension intended for use in the preparation of a spray.	A spray composed of a suspension that contains active and/or inert ingredient(s).
A	C150107	EDQM-HC Routes and Methods of Administration Terminology	C38307	Transplacental Route of Administration	Transplacental	20083000	In utero exposure of an embryo/foetus to a medicinal product administered to the pregnant mother. Comment: This term is not intended to describe an authorised route of administration for use in marketing authorisations, and does not cover intentional administration of a medicinal product to an embryo/foetus. It is intended for use in adeverse event reporting for pharmacovigilance purposes.	Administration of a drug to an embryo in utero via systemic administration of the substance to the pregnant mother. Drugs cross the placenta through passive diffusion, active transport, pinocytosis and filtration. The properties of drugs that determine placental transfer by passive diffusion include molecular weight, pKa, lipid solubility and protein binding. Drugs with molecular weight of over 500 D are transferred incompletely. Drug metabolism and uptake can be altered by placental enzymes.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C87539	Tag Dosage Form	Ear tag	10528000	Solid preparation consisting of a matrix impregnated with active substance(s), which is fixed to a device to be tagged on the animal's ear. The active substance(s) are released by diffusion, by mechanical means or by vaporisation over a period of time.	A pharmaceutical dosage form containing active substance(s) that are delivered via a tag device.
C	C150112	EDQM-HC Administration Method Terminology	C70962	Agent Administration	Administration	0004	Administration of a pharmaceutical product by one of a variety of non-specific methods. To be used only where a more-specific term does not apply.	The act of the dispensing, applying, or tendering a medical product or other agent.
C	C150112	EDQM-HC Administration Method Terminology	C149348	Application Method of Administration	Application	0005	Administration of a pharmaceutical product by placing or spreading it onto the affected area.	The technique of administration of a pharmaceutical product by placing or spreading it onto the affected area.
C	C150112	EDQM-HC Administration Method Terminology	C149352	Bathing Method of Administration	Bathing	0006	Administration of a pharmaceutical product by immersing all or part of the affected area in the product, sometimes for an extended period of time.	The technique of administration of a pharmaceutical product by immersing all or part of the affected area in the product, sometimes for an extended period of time.
C	C150112	EDQM-HC Administration Method Terminology	C149363	Smoking Method of Administration	Burning	0111	Administration of a pharmaceutical product by lighting it in order to evolve smoke that is taken in by the subject.	The technique of administration of a pharmaceutical product by lighting it in order to evolve smoke that is taken in by the subject.
C	C150112	EDQM-HC Administration Method Terminology	C149370	Chewing Method of Administration	Chewing	0007	Administration of a pharmaceutical product by crushing or grinding it with the teeth; after chewing, some products are intended to be swallowed, some are intended to be spat out.	The technique of administration of a pharmaceutical product by crushing or grinding it with the teeth; after chewing, some products are intended to be swallowed, some are intended to be spat out.
C	C150112	EDQM-HC Administration Method Terminology	C149433	Dialysis Method of Administration	Dialysis	0112	Administration of a pharmaceutical product by inclusion in a dialysis system (e.g. haemodialysis, haemofiltration, peritoneal dialysis), as a dialysis or substitution product.	The technique of administration of a pharmaceutical product by inclusion in a dialysis system as a dialysis or substitution product.
C	C150112	EDQM-HC Administration Method Terminology	C149523	Gargling Method of Administration	Gargling	0008	Administration of a pharmaceutical product by rinsing the throat and/or mouth with it, holding it in the throat and keeping it in motion by releasing a stream of air from the lungs; after gargling, the product is usually intended to be spat out.	The technique of administration of a pharmaceutical product by rinsing the throat and/or mouth with it, holding it in the throat and keeping it in motion by releasing a stream of air from the lungs; after gargling, the product is usually intended to be spat out.
C	C150112	EDQM-HC Administration Method Terminology	C149562	Implantation Method of Administration	Implantation	0113	Administration of a pharmaceutical product by placing it within a tissue of the body, usually as part of a surgical procedure.	The technique of administration of a pharmaceutical product by placing it within a tissue of the body, usually as part of a surgical procedure.
C	C150112	EDQM-HC Administration Method Terminology	C149577	Infusion Method of Administration	Infusion	0009	Administration of a pharmaceutical product, usually slowly and in larger volumes than for an injection, by introducing it into the body, usually after puncturing the skin; it is usually administered intravenously, but occasionally by other routes, e.g. subcutaneously.	The technique of administration of a pharmaceutical product, usually slowly and in larger volumes than for an injection, by introducing it into the body, usually after puncturing the skin; it is usually administered intravenously, but occasionally by other routes, e.g. subcutaneously.
C	C150112	EDQM-HC Administration Method Terminology	C149578	Inhalation Method of Administration	Inhalation	0010	Administration of a pharmaceutical product by breathing it into the lungs, usually via the mouth.	The technique of administration of a pharmaceutical product by breathing it into the lungs, usually via the mouth.
C	C150112	EDQM-HC Administration Method Terminology	C149592	Injection Method of Administration	Injection	0011	Administration of a pharmaceutical product by introducing it into the body, usually after puncturing the skin; one or more of a variety of routes may be specified, the most common being intravenous, intramuscular and subcutaneous.	The technique of administration of a pharmaceutical product by introducing it into the body, usually after puncturing the skin; one or more of a variety of routes may be specified, the most common being intravenous, intramuscular and subcutaneous.
C	C150112	EDQM-HC Administration Method Terminology	C149594	Insertion Method of Administration	Insertion	0012	Administration of a pharmaceutical product by placing it into a body cavity, lesion, wound etc.	The technique of administration of a pharmaceutical product by placing it into a body cavity, lesion, wound etc.
C	C150112	EDQM-HC Administration Method Terminology	C149596	Instillation Method of Administration	Instillation	0013	Administration of a pharmaceutical product drop by drop onto or into the affected area.	The technique of administration of a pharmaceutical product drop by drop onto or into the affected area.
C	C150112	EDQM-HC Administration Method Terminology	C149701	Unspecified Method of Administration	Not specified	0020	Administration of a pharmaceutical product by an unspecified method.	The technique of administration of a pharmaceutical product by an unspecified method.
C	C150112	EDQM-HC Administration Method Terminology	C149730	Oral Disintegration Method of Administration	Orodispersion	0014	Administration of a pharmaceutical product by placing it in the mouth and allowing it to dissipate; the product is usually then swallowed.	The technique of administration of a pharmaceutical product by placing it in the mouth and allowing it to dissipate; the product is usually then swallowed.
C	C150112	EDQM-HC Administration Method Terminology	C149887	Rinsing/Washing Method of Administration	Rinsing/washing	0015	Administration of a pharmaceutical product by bringing it into contact with the affected area for a short period of time, e.g. by pouring it over the area and allowing it to drain away, or swilling it around the area and then removing it.	The technique of administration of a pharmaceutical product by bringing it into contact with the affected area for a short period of time, e.g. by pouring it over the area and allowing it to drain away, or swilling it around the area and then removing it.
C	C150112	EDQM-HC Administration Method Terminology	C149950	Spraying Method of Administration	Spraying	0017	Administration of a pharmaceutical product by atomising or otherwise dissipating it into a fine dispersion of particles in air, directing it such that it comes into contact with the affected area.	The technique of administration of a pharmaceutical product by atomizing or otherwise dissipating it into a fine dispersion of particles in air, directing it such that it comes into contact with the affected area.
C	C150112	EDQM-HC Administration Method Terminology	C149961	Sucking Method of Administration	Sucking	0018	Administration of a pharmaceutical product by placing it in the mouth and encouraging it to dissolve in the saliva, usually by moving the tongue.	The technique of administration of a pharmaceutical product by placing it in the mouth and encouraging it to dissolve in the saliva, usually by moving the tongue.
C	C150112	EDQM-HC Administration Method Terminology	C149973	Swallowing Method of Administration	Swallowing	0019	Administration of a pharmaceutical product by introducing it into the stomach via the mouth and oesophagus with a voluntary muscular action.	The technique of administration of a pharmaceutical product by introducing it into the stomach via the mouth and esophagus with a voluntary muscular action.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C96901	Auricular	Auricular	0021	Relating to the ear as the intended site of administration, usually where the pharmaceutical product is intended for action in the auditory canal (external auditory meatus).	Relating to the ear as the intended site of administration, usually where the pharmaceutical product is intended for action in the auditory canal (external auditory meatus).
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149423	Cutaneous/Transdermal	Cutaneous/Transdermal	0022	Relating to the skin or its appendages (e.g. hair, nails) as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the skin, within the skin, or systemically after passing through the skin.	Relating to the skin or its appendages (e.g. hair, nails) as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the skin, within the skin, or systemically after passing through the skin.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C41136	Dental	Dental	0023	Relating to the teeth as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the tooth, inside the tooth, or around the tooth.	Pertaining to a tooth or teeth, or to odontology.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149484	Endocervical	Endocervical	0105	Relating to the cervix uteri as the intended site of administration.	Relating to the cervix uteri as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149494	Environmental	Environmental	0024	Relating to the surroundings in which the target of the pharmaceutical product is found, as the intended site of administration, e.g. an enclosed volume of water or air; usually the product disperses in the area and is subsequently taken up by the subject.	Relating to the surroundings in which the target of the pharmaceutical product is found, as the intended site of administration, e.g. an enclosed volume of water or air; usually the product disperses in the area and is subsequently taken up by the subject.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149497	Extracorporeal	Extracorporeal	0025	Relating to a body substance or tissue as the intended site of administration, after being removed from the body in order to be treated with the pharmaceutical product and then subsequently returned to the body.	Relating to a body substance or tissue as the intended site of administration, after being removed from the body in order to be treated with the pharmaceutical product and then subsequently returned to the body.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13307	Gastric	Gastric	0106	Relating to the stomach as the intended site of administration, where direct administration is achieved using an appropriate device.	Relating to the stomach.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13359	Gastrointestinal	Gastroenteral	0107	Relating to the stomach or duodenum as the intended site of administration, where direct administration is achieved using an appropriate device.	Pertaining to the stomach and intestines.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C25266	Intestinal	Intestinal	0108	Relating to the intestines (duodenum, jejunum, ileum, colon) as the intended site of administration, where direct administration is achieved using an appropriate device.	Of, or related to, or referring to the intestines.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149603	Intramammary	Intramammary	0026	Relating to the milk-producing organs (mammae) of a female mammal as the intended site of administration, to describe veterinary-only pharmaceutical products that are administered via the teat canal.	Relating to the milk-producing organs (mammae) of a female mammal as the intended site of administration, to describe veterinary-only pharmaceutical products that are administered via the teat canal.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13352	Intraperitoneal	Intraperitoneal	0109	Relating to the peritoneal cavity as the intended site of administration.	Relating to the peritoneal cavity as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C96903	Intrauterine	Intrauterine	0027	Relating to the cavity of the uterus as the intended site of administration.	Relating to the cavity of the uterus as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149623	Intravesical/Urethral	Intravesical/Urethral	0028	Relating to the urinary bladder or the urethra (the urogenital canal, connecting the bladder to the outside of the body) as the intended site of administration.	Relating to the urinary bladder or the urethra as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C27958	Nasal	Nasal	0029	Relating to the nose as the intended site of administration, including where the pharmaceutical product is intended for local action in the nasal cavity or for systemic action after absorption through the mucous membrane; the lower respiratory tract is excluded.	In reference to the nose.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C87163	Ocular	Ocular	0030	Relating to the eye as the intended site of administration, including where the pharmaceutical product is intended for action on the surface of the eye or conjunctiva, around the eye, or within the eye.	Of or relating to the eye.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149702	Oculonasal	Oculonasal	0110	Relating to the eyes and nares of a bird as the intended site of administration.	Relating to the eyes and nares of a bird as the intended site of administration.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C25311	Oral	Oral	0031	Relating to the mouth as the intended site of administration, but where the pharmaceutical product is administered with the intention of passing into the stomach via the oesophagus; the mucosa of the mouth itself is not the intended site of action (see oromucosal).	Of, or relating to, or affecting, or for use in the mouth.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C149731	Oromucosal	Oromucosal	0032	Relating to the mouth as the intended site of administration, where the pharmaceutical product is administered with the intention of acting on the mucosa of the mouth, whether for local or systemic use.	Relating to the mouth as the intended site of administration, where the pharmaceutical product is administered with the intention of acting on the mucosa of the mouth, whether for local or systemic use.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C150414	Parenteral	Parenteral	0033	Relating to the internal body as the intended site of administration, other than the natural openings and cavities such as the gastrointestinal tract, auditory canal, nasal cavity, lungs, etc.; the pharmaceutical product is usually administered by breaking the skin, such as by injection, infusion, and implantation.	Relating to the internal body as the intended site of administration, other than the natural openings and cavities such as the gastrointestinal tract, auditory canal, nasal cavity, lungs, etc.; the pharmaceutical product is usually administered by breaking the skin, such as by injection, infusion, and implantation.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13304	Pulmonary	Pulmonary	0034	Relating to the lungs as the intended site of administration, where the pharmaceutical product is administered, usually by inhalation, for local action in the lower respiratory tract or for systemic action after absorption via the lower respiratory tract.	Relating to the lungs as the intended site of administration, where the pharmaceutical product is administered, usually by inhalation, for local action in the lower respiratory tract or for systemic action after absorption via the lower respiratory tract.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C25224	Rectal	Rectal	0035	Relating to the rectum as the intended site of administration, where the pharmaceutical product is administered via the anal canal, for local action in the rectum or for systemic action after absorption via the rectum.	Of or pertaining to the rectum.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C150004	Unknown/Miscellaneous Anatomical Location	Unknown/Miscellaneous	0037	Relating to various unspecified parts of the body as the intended site of administration, or where the intended site of administration is unknown or not specified.	Relating to various unspecified parts of the body as the intended site of administration, or where the intended site of administration is unknown or not specified.
C	C150114	EDQM-HC Intended Site of Administration Terminology	C13309	Vaginal	Vaginal	0036	Relating to the vagina as the intended site of administration, where the pharmaceutical product is administered via the vaginal opening, usually for local action in the vagina but sometimes for systemic action after absorption via the vagina.	Of or relating to the vagina.
C	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C42927	Extended Release Tablet Dosage Form	Prolonged-release tablet	10226000	Solid single-dose preparation consisting of a tablet showing a slower release of the active substance(s) than that of a conventional-release tablet. Prolonged release is achieved by a special formulation design and/or manufacturing method. Prolonged-release tablets are intended for oral use.	A tablet designed to release active and/or inert ingredient(s) at a controlled, prolonged rate so as to reduce dosing frequency.
C	C150115	EDQM-HC Release Characteristics Terminology	C149409	Conventional Release Mechanism of Action	Conventional	0047	Release of the substance(s) in a way that is not deliberately modified by a special formulation design and/or manufacturing method.	Release of the substance(s) in a way that is not deliberately modified by a special formulation design and/or manufacturing method.
C	C150115	EDQM-HC Release Characteristics Terminology	C149427	Delayed Release Mechanism of Action	Delayed	0044	Release of the substance(s) at a later time than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method; enteric-coated and other gastro-resistant products are included.	Release of the substance(s) at a later time than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method; enteric-coated and other gastro-resistant products are included.
C	C150115	EDQM-HC Release Characteristics Terminology	C149662	Modified-release Mechanism of Action	Modified	0046	Release of the substance(s) in a way that differs from that which would be achieved with a conventional-release product, which is achieved by a special formulation design and/or manufacturing method, but which is not classified as delayed-release or prolonged-release; pulsatile-release products are included.	Release of the substance(s) in a way that differs from that which would be achieved with a conventional-release product, which is achieved by a special formulation design and/or manufacturing method, but which is not classified as delayed-release or prolonged-release; pulsatile-release products are included.
C	C150115	EDQM-HC Release Characteristics Terminology	C149870	Prolonged Release Mechanism of Action	Prolonged	0045	Release of the substance(s) over a longer duration than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method.	Release of the substance(s) over a longer duration than would be achieved with a conventional-release product, achieved by a special formulation design and/or manufacturing method.
C	C150115	EDQM-HC Release Characteristics Terminology	C150002	Unknown Mechanism of Action	Unknown	0048	Release of the substance(s) in a way that is unknown or not specified.	Release of the substance(s) in a way that is unknown or not specified.
C	C150116	EDQM-HC State of Matter Terminology	C45299	Gas	Gas	0100	A state of matter consisting of molecules in an elastic aeriform fluid, separated from one another and with freedom of movement, no independent shape or volume and the ability to expand indefinitely.	A fluid in the gaseous state having neither independent shape nor volume and being able to expand indefinitely.
C	C150116	EDQM-HC State of Matter Terminology	C45298	Liquid	Liquid	0099	A state of matter consisting of molecules in a non-rigid structure that retains its volume but conforms to the shape of any container applying pressure to it, and is subject to flow.	A substance in the fluid state of matter having no fixed shape but a fixed volume.
C	C150116	EDQM-HC State of Matter Terminology	C149895	Semi-solid	Semi-solid	0098	A state of matter consisting of molecules in a non-rigid structure that can retain its shape and volume but that is not resistant to such change.	A state of matter consisting of molecules in a non-rigid structure that can retain its shape and volume but that is not resistant to such change.
C	C150116	EDQM-HC State of Matter Terminology	C45300	Solid	Solid	0097	A state of matter consisting of molecules in a rigid structure that is resistant to change in shape or volume.	The state in which a substance has no tendency to flow under moderate stress; resists forces (such as compression) that tend to deform it; and retains a definite size and shape.
C	C150116	EDQM-HC State of Matter Terminology	C150000	Unclear State of Matter	Unclear	0101	A state of matter of unknown, unspecified or variable physical characteristics.	A state of matter of unknown, unspecified or variable physical characteristics.
C	C150117	EDQM-HC Transformation Terminology	C64657	Dilute	Dilution	0038	Transformation of a concentrate into a liquid of greater volume and lower concentration by mixing it with a specified solvent.	To reduce in strength or concentration, especially by the addition of water.
C	C150117	EDQM-HC Transformation Terminology	C150035	Dispersion Activity	Dispersion	0039	Transformation of a solid or gas into a dispersion or suspension by mixing it with a specified liquid.	Transformation of a solid or gas into a dispersion or suspension by mixing it with a specified liquid.
C	C150117	EDQM-HC Transformation Terminology	C113023	Dissolution Mixing	Dissolution	0040	Transformation of a solid into a solution by mixing it with a specified liquid.	Mixing by adding solids to agitated liquids.
C	C150117	EDQM-HC Transformation Terminology	C64925	Mix	Mixing	0041	Transformation of a product into another product by mixing with a specified product.	To bring or combine together or with something else; add as an additional element or part.
C	C150117	EDQM-HC Transformation Terminology	C149700	No Transformation	No transformation	0042	No transformation of the product takes place.	No transformation of the product takes place.
C	C150117	EDQM-HC Transformation Terminology	C150003	Unknown Transformation	Unknown	0043	It is unknown whether any transformation of the product takes place.	It is unknown whether any transformation of the product takes place.
C	C150109	EDQM-HC Container Terminology	C43168	Blister Pack	Blister	30007000	Container (usually multidose) consisting of two layers of which one is shaped to contain the individual doses. Strips and unit-dose blisters are excluded.	A package that consists of molded plastic or laminate that has indentations (viewed as 'blisters' when flipped) into which a dosage form, is placed. A covering, usually of laminated material, is then sealed to the molded part. A strip pack is a specialized type of blister pack where there are no pre-formed or molded parts; in this case there are two flexible layers that are sealed with the dosage form in between. Suppositories that are strip packed between two layers of foil are also considered a blister pack.
C	C150109	EDQM-HC Container Terminology	C149860	Pre-filled Injector	Pre-filled injector	13063000	Filled container, usually fitted with an injection needle, containing a sterile, single-dose parenteral preparation. This term is only to be used when a more-specific term such as 'Pre-filled syringe' or 'Pre-filled pen' is not appropriate. Comment: This term may be used to describe, for example, an item of packaging that is intended to be used by puncturing the skin and squeezing a small reservoir to administer its contents.	Filled container, usually fitted with an injection needle, containing a sterile, single-dose parenteral preparation.
C	C150109	EDQM-HC Container Terminology	C149862	Pre-filled Oral Syringe	Pre-filled oral syringe	13073000	Filled container for administering a liquid or semi-solid pharmaceutical form to the oral cavity, containing the final preparation in one compartment, or the components necessary for its preparation in different compartments. Comment: For certain products that are usually associated with administration by injection, such as vaccines, the term "Pre-filled oral applicator" may be used instead in order to reduce any risk of administration by injection.	Filled container for administering a liquid or semi-solid pharmaceutical form to the oral cavity, containing the final preparation in one compartment, or the components necessary for its preparation in different compartments.
C	C150107	EDQM-HC Routes and Methods of Administration Terminology	C38205	Endocervical Route of Administration	Endocervical use	20006000	Administration of a medicinal product to the cervix uteri.	Administration of the drug within the canal of the cervix uteri.
C	C150110	EDQM-HC Administration Device Terminology	C50296	Pipette Device	Pipette	30046000	Administration device, tubular, used for the administration in drops or in accurately measured quantity of liquid pharmaceutical forms.	A measuring device, traditionally including a graduated tube, designed for the accurate transfer of liquid volumes.
A	C150108	EDQM-HC Closure Terminology	C154642	Pipette Closure Device	Pipette applicator	30047000	Closure with pipette.	Closure with pipette.
A	C150103	EDQM-HC Pharmaceutical Dosage Form Terminology	C154663	Powder for Vaginal Solution	Powder for vaginal solution	13111000	Solid preparation consisting of one or more powders, including freeze-dried powders, intended to be dissolved in the specified liquid to obtain a vaginal solution.	Solid preparation consisting of one or more powders, including freeze-dried powders, intended to be dissolved in the specified liquid to obtain a vaginal solution.